Las Vegas Cafe

Lil Rita's Grill House on East Tyler Avenue serves Thai food, despite the name. Texas Highways called it authentic Thai cuisine, and the restaurant takes orders online.

Los Asados serves Mexican food on South Ware Road, with a sister restaurant in Harlingen that has been open for more than 30 years.

Los Norteños is a Mexican restaurant on West Jackson Avenue in Harlingen that opens at 6 AM for breakfast.

Los Salseados de Mazatlán on North 10th Street serves Sinaloa-style seafood, from pulpo zarandeado and aguachile to cocteles and tostadas; the brand began in Mexico and this is its U.S. location.

Mesquite Valley Smokehouse is a full-service barbecue restaurant in downtown Harlingen that hand-blends its own spices for brisket and ribs, with sandwiches, brisket fries and Valley nachos on the menu.

Momole in The Mercado District serves Mexican food built around 12 kinds of mole, and in 2026 it received an authenticity award as the only restaurant in South Texas to earn it.

Pepe's Mexican Restaurant on South 77 Sunshine Strip has served Mexican food in Harlingen since 1994, according to the City of Harlingen.

Pho #1 on South Expressway 83 serves pho and other Vietnamese and Thai dishes, with takeout and delivery. It's open Tuesday through Sunday and closed on Mondays.